Regulatory T cells (Tregs) play an important role in immunoregulation and have been shown in animal models to promote transplantation tolerance and curb autoimmunity following their adoptive transfer.The safety and potential therapeutic efficacy of these cells has already been reported in Phase I trials of bone marrow transplantation and type I dia

Purpose: To describe the clinical and morphologic changes in the ocular surface microstructure of patients affected with moderate-to-severe Atopic Dermatitis (AD) before and during Dupilumab treatment.Methods: This is a monocentric observational study on thirty-three patients affected with AD before and during Dupilumab treatment.All patients under

Meloidogyne graminicola has emerged as one of the most destructive plant-parasitic nematodes affecting rice (Oryza sativa) production worldwide.Resistance to M.graminicola in rice could be the most effective option for its management.However, sources of germplasm with resistance to M.graminicola in rice remain limited.Here, we describe the root att

The article deals with the issue of retirement in contemporary Polish society.The analysis is based on a aquarium qualitative research project conducted with people who had formally retired within the previous five years.The process of retiring is one of the most important turning points in the life course.The aim is to look more carefully at the e

Several pyrazolo[1,5-a]pyrimidine, triazolo[1,5-a]pyrimidine, pyrido[1,2-a]-benzimidazole, pyrimido[1,2-a]benzimidazole, pyrazolo[5,1-c]triazine, triazolo[5,1-c]-triazine, triazino[4,3-a]benzimidazole and 1,3,4-thiadiazole derivatives Poles were synthesized via the reactions of (E)-3-oxo-5-phenylpent-4-enenitrile and the versatile, hitherto unrepor